File Name: myxedema coma diagnosis and treatment .zip
A forgotten but important risk factor for severe hyponatremia: myxedema coma. Email: benankasapoglu hotmail. Hypothyroidism is one of the most prevalent endocrine diseases.
This is a preview of subscription content, access via your institution. Rent this article via DeepDyve. Nicoloff JT. Thyroid storm and myxedema coma. Med Clin North Am ;— Google Scholar.
SARS-CoV-2 infection is associated with significant lung and cardiac morbidity but there is a limited understanding of the endocrine manifestations of coronavirus disease COVID A year-old woman with a history of small cell lung cancer presented with hypothermia, hypotension, decreased respiratory rate, and a Glasgow Coma Scale score of 5. The patient was intubated and administered vasopressors. Laboratory investigation showed elevated thyrotropin, very low free thyroxine, elevated thyroid peroxidase antibody, and markedly elevated inflammatory markers. Computed tomography showed pulmonary embolism and peripheral ground-glass opacities in the lungs. While treatment with intravenous hydrocortisone and levothyroxine were begun the patient developed a junctional escape rhythm.
Myxedema coma: four patients diagnosed at the Internal Medicine Department of the Dr. Negrin University Hospital in Spain. Myxedema coma is a rare complication of hypothyroidism.
Louis, and Assistant in Medicine, Washington University School of Medicine: A year-old white woman was admitted to Jewish Hospital with a two-day history of abdominal pain, vomiting of bilious material, and diarrhea. There was no previous history of weight gain, cold intolerance, or constipation. In the past few months she had had some drowsiness and a gradual decrease in mental acuity. The voice was deeply pitched and hoarse, the skin was dry, and the scalp hair was coarse. Rales were heard at the bases of both lungs. Examination of the abdomen revealed diffuse involuntary rigidity, rebound tenderness, and high-pitched, rushing bowel sounds.
Myxedema coma, the extreme manifestation of hypothyroidism, is an uncommon but potentially lethal condition. Patients with hypothyroidism may exhibit a number of physiologic alterations to compensate for the lack of thyroid hormone. If these homeostatic mechanisms are overwhelmed by factors such as infection, the patient may decompensate into myxedema coma. Patients with hypothyroidism typically have a history of fatigue, weight gain, constipation and cold intolerance. Physicians should include hypothyroidism in the differential diagnosis of every patient with hyponatremia.